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Redefining Interventional Cardiology with Scalable AI Innovation

ComKardia is building an AI-powered decision-support platform for stent-based procedures. Using a patient-specific digital twin and scenario-based analysis, we help cardiologists plan treatment approaches with greater precision, efficiency, and consistency. The platform is designed to reduce variability and support scalable deployment across catheterization labs.

ComKardia Platform & Workflow

Fully Integrated Insight & Intelligence for Next Generation PCI

Clinical Problem

Percutaneous Coronary Intervention (PCI)

PCI is a common procedure for treating coronary artery disease.

Angiography-guided PCI results in 5-30% adverse clinical events (depending on procedure complexity), including heart attacks, hospital readmissions, repeat stent procedures, and death.

IVUS/OCT-Guided PCI

IVUS/OCT-guided PCI reduces adverse events by up to 50%.

Despite its benefits, global market penetration of IVUS/OCT in PCI remains below 15-20%.

A man in a white lab coat working at a computer, viewing a 3D model on the screen in a laboratory or office setting.

Solution

ComKardia is developing AI decision support for stent-based procedures. Using intravascular imaging and a patient-specific digital twin, the platform supports scenario-based planning for stent selection, sizing, and placement. The goal is faster, more consistent decisions that scale across cath labs.

IVUS/OCT integration in PCI processes through:

Automated lumen segmentation

Co-registration with angiography

3D reconstruction of anatomy

Fractional flow reserve (FFR)

Automatic plaque material characterization

Real-time clinical decision support system

ComKardia’s Competitive Edge

ComKardia is redefining PCI optimization through predictive and therapy-guiding intelligence. We combine physics-based digital twins, AI-driven simulation, and clinical validation to deliver a first-in-class decision support platform that transforms how interventional cardiologists plan and execute procedures.

Clinical Edge

Technology & IP Edge

Data, Partnerships & Market Edge

Predictive + prescriptive CDSS: Only system that not only predicts stent expansion but recommends lesion preparation strategies beyond NC balloons.

Extensive digital twin library: >100,000 validated simulations across calcified, fibrotic, and mixed plaques.

Multimodal imaging integration (IVUS/OCT + angiography) vs. static single-modality competitors.

Ongoing multicenter validation in U.S. and Europe.

Clinical Edge

Technology & IP Edge

Data, Partnerships & Market Edge

Predictive + prescriptive CDSS: Only system that not only predicts stent expansion but recommends lesion preparation strategies beyond NC balloons.

Extensive digital twin library: >100,000 validated simulations across calcified, fibrotic, and mixed plaques.

Multimodal imaging integration (IVUS/OCT + angiography) vs. static single-modality competitors.

Ongoing multicenter validation in U.S. and Europe.

Clinical Edge

Technology & IP Edge

Data, Partnerships & Market Edge

Predictive + prescriptive CDSS: Only system that not only predicts stent expansion but recommends lesion preparation strategies beyond NC balloons.

Extensive digital twin library: >100,000 validated simulations across calcified, fibrotic, and mixed plaques.

Multimodal imaging integration (IVUS/OCT + angiography) vs. static single-modality competitors.

Ongoing multicenter validation in U.S. and Europe.