Clinical Validation
These publications affirm ComKardia’s clinical utility, technical rigor, and scalability across diverse imaging modalities, anatomical complexities, and procedural contexts—establishing a strong foundation for commercial deployment and regulatory engagement.
Publications
Publications
Publications
Wu W, Banga A, Oguz UM, Zhao S, Thota AK, Gadamidi VK, Dasari VS, Samant S, Watanabe Y, Murasato Y, Chatzizisis YS. Experimental validation and clinical feasibility of 3D reconstruction of coronary artery bifurcation stents using intravascular ultrasound. PLoS One. 2024 Apr 16;19(4):e0300098.
Wu W, Banga A, Oguz UM, Zhao S, Thota AK, Gadamidi VK, Dasari VS, Samant S, Watanabe Y, Murasato Y, Chatzizisis YS. Experimental validation and clinical feasibility of 3D reconstruction of coronary artery bifurcation stents using intravascular ultrasound. PLoS One. 2024 Apr 16;19(4):e0300098.
Wu W, Banga A, Oguz UM, Zhao S, Thota AK, Gadamidi VK, Dasari VS, Samant S, Watanabe Y, Murasato Y, Chatzizisis YS. Experimental validation and clinical feasibility of 3D reconstruction of coronary artery bifurcation stents using intravascular ultrasound. PLoS One. 2024 Apr 16;19(4):e0300098.
Wu W, Roby M, Banga A, Oguz UM, Gadamidi VK, Hasini Vasa C, Zhao S, Dasari VS, Thota AK, Tanweer S, Lee C, Kassab GS, Chatzizisis YS. Rapid automated lumen segmentation of coronary optical coherence tomography images followed by 3D reconstruction of coronary arteries. J Med Imaging (Bellingham). 2024 Jan;11(1):014004.
Wu W, Roby M, Banga A, Oguz UM, Gadamidi VK, Hasini Vasa C, Zhao S, Dasari VS, Thota AK, Tanweer S, Lee C, Kassab GS, Chatzizisis YS. Rapid automated lumen segmentation of coronary optical coherence tomography images followed by 3D reconstruction of coronary arteries. J Med Imaging (Bellingham). 2024 Jan;11(1):014004.
Wu W, Roby M, Banga A, Oguz UM, Gadamidi VK, Hasini Vasa C, Zhao S, Dasari VS, Thota AK, Tanweer S, Lee C, Kassab GS, Chatzizisis YS. Rapid automated lumen segmentation of coronary optical coherence tomography images followed by 3D reconstruction of coronary arteries. J Med Imaging (Bellingham). 2024 Jan;11(1):014004.
Samant S, Bakhos JJ, Wu W, Zhao S, Kassab GS, Khan B, Panagopoulos A, Makadia J, Oguz UM, Banga A, Fayaz M, Glass W, Chiastra C, Burzotta F, LaDisa JF Jr,Iaizzo P, Murasato Y, Dubini G, Migliavacca F, Mickley T, Bicek A, Fontana J, West NEJ, Mortier P, Boyers PJ, Gold JP, Anderson DR, Tcheng JE, Windle JR,Samady H, Jaffer FA, Desai NR, Lansky A, Mena-Hurtado C, Abbott D, Brilakis ES, Lassen JF, Louvard Y, Stankovic G, Serruys PW, Velazquez E, Elias P, Bhatt DL, Dangas G, Chatzizisis YS. Artificial Intelligence, Computational Simulations, and Extended Reality in Cardiovascular Interventions. JACC Cardiovasc Interv. 2023 Oct 23;16(20):2479-2497.
Samant S, Bakhos JJ, Wu W, Zhao S, Kassab GS, Khan B, Panagopoulos A, Makadia J, Oguz UM, Banga A, Fayaz M, Glass W, Chiastra C, Burzotta F, LaDisa JF Jr,Iaizzo P, Murasato Y, Dubini G, Migliavacca F, Mickley T, Bicek A, Fontana J, West NEJ, Mortier P, Boyers PJ, Gold JP, Anderson DR, Tcheng JE, Windle JR,Samady H, Jaffer FA, Desai NR, Lansky A, Mena-Hurtado C, Abbott D, Brilakis ES, Lassen JF, Louvard Y, Stankovic G, Serruys PW, Velazquez E, Elias P, Bhatt DL, Dangas G, Chatzizisis YS. Artificial Intelligence, Computational Simulations, and Extended Reality in Cardiovascular Interventions. JACC Cardiovasc Interv. 2023 Oct 23;16(20):2479-2497.
Samant S, Bakhos JJ, Wu W, Zhao S, Kassab GS, Khan B, Panagopoulos A, Makadia J, Oguz UM, Banga A, Fayaz M, Glass W, Chiastra C, Burzotta F, LaDisa JF Jr,Iaizzo P, Murasato Y, Dubini G, Migliavacca F, Mickley T, Bicek A, Fontana J, West NEJ, Mortier P, Boyers PJ, Gold JP, Anderson DR, Tcheng JE, Windle JR,Samady H, Jaffer FA, Desai NR, Lansky A, Mena-Hurtado C, Abbott D, Brilakis ES, Lassen JF, Louvard Y, Stankovic G, Serruys PW, Velazquez E, Elias P, Bhatt DL, Dangas G, Chatzizisis YS. Artificial Intelligence, Computational Simulations, and Extended Reality in Cardiovascular Interventions. JACC Cardiovasc Interv. 2023 Oct 23;16(20):2479-2497.
Wu W, Oguz UM, Banga A, Zhao S, Thota AK, Gadamidi VK, Vasa CH, Harmouch KM, Naser A, Tieliwaerdi X, Chatzizisis YS. 3D reconstruction of coronary artery bifurcations from intravascular ultrasound and angiography. Sci Rep. 2023 Aug 10;13(1):13031.
Wu W, Oguz UM, Banga A, Zhao S, Thota AK, Gadamidi VK, Vasa CH, Harmouch KM, Naser A, Tieliwaerdi X, Chatzizisis YS. 3D reconstruction of coronary artery bifurcations from intravascular ultrasound and angiography. Sci Rep. 2023 Aug 10;13(1):13031.
Wu W, Oguz UM, Banga A, Zhao S, Thota AK, Gadamidi VK, Vasa CH, Harmouch KM, Naser A, Tieliwaerdi X, Chatzizisis YS. 3D reconstruction of coronary artery bifurcations from intravascular ultrasound and angiography. Sci Rep. 2023 Aug 10;13(1):13031.
Wu W, Oguz UM, Banga A, Zhao S, Thota AK, Gadamidi VK, Vasa CH, Harmouch KM, Naser A, Tieliwaerdi X, Chatzizisis YS. 3D reconstruction of coronary artery bifurcations from intravascular ultrasound and angiography. Sci Rep. 2023 Aug 10;13(1):13031. aChatzizisis YS, Makadia J, Zhao S, Panagopoulos A, Sharzehee M, Khan B, Samant S, Fayaz M, Pandya J, Akkad H, Pavlides G, O'Leary E, Wu W. First-in- Human Computational Preprocedural Planning of Left Main Interventions Using a New Everolimus-Eluting Stent. JACC Case Rep. 2022 Mar 16;4(6):325-335.
Wu W, Oguz UM, Banga A, Zhao S, Thota AK, Gadamidi VK, Vasa CH, Harmouch KM, Naser A, Tieliwaerdi X, Chatzizisis YS. 3D reconstruction of coronary artery bifurcations from intravascular ultrasound and angiography. Sci Rep. 2023 Aug 10;13(1):13031. aChatzizisis YS, Makadia J, Zhao S, Panagopoulos A, Sharzehee M, Khan B, Samant S, Fayaz M, Pandya J, Akkad H, Pavlides G, O'Leary E, Wu W. First-in- Human Computational Preprocedural Planning of Left Main Interventions Using a New Everolimus-Eluting Stent. JACC Case Rep. 2022 Mar 16;4(6):325-335.
Wu W, Oguz UM, Banga A, Zhao S, Thota AK, Gadamidi VK, Vasa CH, Harmouch KM, Naser A, Tieliwaerdi X, Chatzizisis YS. 3D reconstruction of coronary artery bifurcations from intravascular ultrasound and angiography. Sci Rep. 2023 Aug 10;13(1):13031. aChatzizisis YS, Makadia J, Zhao S, Panagopoulos A, Sharzehee M, Khan B, Samant S, Fayaz M, Pandya J, Akkad H, Pavlides G, O'Leary E, Wu W. First-in- Human Computational Preprocedural Planning of Left Main Interventions Using a New Everolimus-Eluting Stent. JACC Case Rep. 2022 Mar 16;4(6):325-335.
Zhao S, Wu W, Samant S, Khan B, Kassab GS, Watanabe Y, Murasato Y, Sharzehee M, Makadia J, Zolty D, Panagopoulos A, Burzotta F, Migliavacca F, Johnson TW, Lefevre T, Lassen JF, Brilakis ES, Bhatt DL, Dangas G, Chiastra C, Stankovic G, Louvard Y, Chatzizisis YS. Patient-specific computational simulation of coronary artery bifurcation stenting. Sci Rep. 2021 Aug 13;11(1):16486.
Zhao S, Wu W, Samant S, Khan B, Kassab GS, Watanabe Y, Murasato Y, Sharzehee M, Makadia J, Zolty D, Panagopoulos A, Burzotta F, Migliavacca F, Johnson TW, Lefevre T, Lassen JF, Brilakis ES, Bhatt DL, Dangas G, Chiastra C, Stankovic G, Louvard Y, Chatzizisis YS. Patient-specific computational simulation of coronary artery bifurcation stenting. Sci Rep. 2021 Aug 13;11(1):16486.
Zhao S, Wu W, Samant S, Khan B, Kassab GS, Watanabe Y, Murasato Y, Sharzehee M, Makadia J, Zolty D, Panagopoulos A, Burzotta F, Migliavacca F, Johnson TW, Lefevre T, Lassen JF, Brilakis ES, Bhatt DL, Dangas G, Chiastra C, Stankovic G, Louvard Y, Chatzizisis YS. Patient-specific computational simulation of coronary artery bifurcation stenting. Sci Rep. 2021 Aug 13;11(1):16486.
Wu W, Khan B, Sharzehee M, Zhao S, Samant S, Watanabe Y, Murasato Y, Mickley T, Bicek A, Bliss R, Valenzuela T, Iaizzo PA, Makadia J, Panagopoulos A, Burzotta F, Samady H, Brilakis ES, Dangas GD, Louvard Y, Stankovic G, Dubini G, Migliavacca F, Kassab GS, Edelman ER, Chiastra C, Chatzizisis YS. Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinical feasibility. Sci Rep. 2021 Jun 10;11(1):12252.
Wu W, Khan B, Sharzehee M, Zhao S, Samant S, Watanabe Y, Murasato Y, Mickley T, Bicek A, Bliss R, Valenzuela T, Iaizzo PA, Makadia J, Panagopoulos A, Burzotta F, Samady H, Brilakis ES, Dangas GD, Louvard Y, Stankovic G, Dubini G, Migliavacca F, Kassab GS, Edelman ER, Chiastra C, Chatzizisis YS. Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinical feasibility. Sci Rep. 2021 Jun 10;11(1):12252.
Wu W, Khan B, Sharzehee M, Zhao S, Samant S, Watanabe Y, Murasato Y, Mickley T, Bicek A, Bliss R, Valenzuela T, Iaizzo PA, Makadia J, Panagopoulos A, Burzotta F, Samady H, Brilakis ES, Dangas GD, Louvard Y, Stankovic G, Dubini G, Migliavacca F, Kassab GS, Edelman ER, Chiastra C, Chatzizisis YS. Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinical feasibility. Sci Rep. 2021 Jun 10;11(1):12252.
Samant S, Wu W, Zhao S, Khan B, Sharzehee M, Panagopoulos A, Makadia J, Mickley T, Bicek A, Boismier D, Murasato Y, Chatzizisis YS. Computational and experimental mechanical performance of a new everolimus-eluting stent purpose- built for left main interventions. Sci Rep. 2021 Apr 22;11(1):8728.
Samant S, Wu W, Zhao S, Khan B, Sharzehee M, Panagopoulos A, Makadia J, Mickley T, Bicek A, Boismier D, Murasato Y, Chatzizisis YS. Computational and experimental mechanical performance of a new everolimus-eluting stent purpose- built for left main interventions. Sci Rep. 2021 Apr 22;11(1):8728.
Samant S, Wu W, Zhao S, Khan B, Sharzehee M, Panagopoulos A, Makadia J, Mickley T, Bicek A, Boismier D, Murasato Y, Chatzizisis YS. Computational and experimental mechanical performance of a new everolimus-eluting stent purpose- built for left main interventions. Sci Rep. 2021 Apr 22;11(1):8728.
Wu W, Samant S, de Zwart G, Zhao S, Khan B, Ahmad M, Bologna M, Watanabe Y, Murasato Y, Burzotta F, Brilakis ES, Dangas G, Louvard Y, Stankovic G, Kassab GS, Migliavacca F, Chiastra C, Chatzizisis YS. 3D reconstruction of coronary artery bifurcations from coronary angiography and optical coherence tomography: feasibility, validation, and reproducibility. Sci Rep. 2020 Oct 22;10(1):18049.
Wu W, Samant S, de Zwart G, Zhao S, Khan B, Ahmad M, Bologna M, Watanabe Y, Murasato Y, Burzotta F, Brilakis ES, Dangas G, Louvard Y, Stankovic G, Kassab GS, Migliavacca F, Chiastra C, Chatzizisis YS. 3D reconstruction of coronary artery bifurcations from coronary angiography and optical coherence tomography: feasibility, validation, and reproducibility. Sci Rep. 2020 Oct 22;10(1):18049.
Wu W, Samant S, de Zwart G, Zhao S, Khan B, Ahmad M, Bologna M, Watanabe Y, Murasato Y, Burzotta F, Brilakis ES, Dangas G, Louvard Y, Stankovic G, Kassab GS, Migliavacca F, Chiastra C, Chatzizisis YS. 3D reconstruction of coronary artery bifurcations from coronary angiography and optical coherence tomography: feasibility, validation, and reproducibility. Sci Rep. 2020 Oct 22;10(1):18049.